{ "_id": "6a1bfc6b1d7bb097a0a28170", "Package": "PWEALL", "Type": "Package", "Version": "1.3.0.1", "Date": "2018-10-18", "Title": "Design and Monitoring of Survival Trials Accounting for Complex\nSituations", "Description": "Calculates various functions needed for design and\nmonitoring survival trials accounting for complex situations\nsuch as delayed treatment effect, treatment crossover,\nnon-uniform accrual, and different censoring distributions\nbetween groups. The event time distribution is assumed to be\npiecewise exponential (PWE) distribution and the entry time is\nassumed to be piecewise uniform distribution. As compared with\nVersion 1.2.1, two more types of hybrid crossover are added. A\nbug is corrected in the function \"pwecx\" that calculates the\ncrossover-adjusted survival, distribution, density, hazard and\ncumulative hazard functions. Also, to generate the\ncrossover-adjusted event time random variable, a more efficient\nalgorithm is used and the output includes crossover indicators.", "Authors@R": "c(\nperson(given=\"Xiaodong\", family=\"Luo\", email = \"Xiaodong.Luo@sanofi.com\", role =c(\"aut\", \"cre\")),\nperson(given=\"Xuezhou\", family=\"Mao\", role = \"ctb\"),\nperson(given=\"Xun\", family=\"Chen\", role = \"ctb\"),\nperson(given=\"Hui\", family=\"Quan\", role = \"ctb\"),\nperson(\"Sanofi\", role = \"cph\"))", "License": "GPL (>= 2)", "RoxygenNote": "5.0.1", "NeedsCompilation": "yes", "Packaged": { "Date": "2026-05-31 09:09:32 UTC", "User": "root" }, "Author": "Xiaodong Luo [aut, cre], Xuezhou Mao [ctb], Xun Chen [ctb], Hui\nQuan [ctb], Sanofi [cph]", "Maintainer": "Xiaodong Luo ", "Repository": "https://marvels2031.r-universe.dev", "Date/Publication": "2023-08-09 06:32:06 UTC", "RemoteUrl": "https://github.com/cran/PWEALL", "RemoteRef": "HEAD", "RemoteSha": "d4c6df009fc16ab16ceb1cb5cae9cabde76dadac", 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"innervar", "title": "A utility function to calculate the inner integration of the overall variance", "topics": [ "innervar" ] }, { "page": "instudyfindt", "title": "calculate the timeline in study when some or all subjects have entered", "topics": [ "instudyfindt" ] }, { "page": "ovbeta", "title": "calculate the overall log hazard ratio", "topics": [ "ovbeta" ] }, { "page": "overallcov", "title": "calculate the overall covariance", "topics": [ "overallcov" ] }, { "page": "overallcovp1", "title": "calculate the first part of the overall covariance", "topics": [ "overallcovp1" ] }, { "page": "overallcovp2", "title": "calculate the other parts of the overall covariance", "topics": [ "overallcovp2" ] }, { "page": "overallvar", "title": "calculate the overall variance", "topics": [ "overallvar" ] }, { "page": "pwe", "title": "Piecewise exponential distribution: hazard, cumulative hazard, density, distribution, survival", "topics": [ "pwe" ] }, { "page": "pwecx", "title": "Various function 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